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Share 35. What are the relative concentrations of large anions, Ca2, Na, K\', Cr

ID: 3483793 • Letter: S

Question

Share 35. What are the relative concentrations of large anions, Ca2, Na, K', Cr (high or low) in and out of the cell at resting membrane potential? Ion Ca2+ Na At RMP linside] (low or high) At RMP loutsidel (low or high) Cl Anions What maintains the resting membrane potential? Does that process require ATP? 36. What is the resting membrane potential in mV? happens to the membrane potential in mV (more negative or more positive) when you: Open a Cl channel? -Open a Ca channel? -Open a Na channel? -Open a K channel? 37. What 38. Is a neuron more or less likely to fire (reach threshold): - if the membrane potential is more negative? (ex: change from -70mV to -80mV) - if the membrane potential is more positive? (ex: change from -70m V to -60mV)

Explanation / Answer

35. The resting membrane potential of a cell is negative and it is maintained by sodium/potassium pump.

Ions Inside outside

Ca++ low high

Na+ low high

K+ high low

Cl- high low

Anaions High low

Sodium potassium pump maintain the resting membrane potential. This pump causes movement 3 soium ion out to the cell and only 2 potassium inside the cell. This pump causes movement of sodium and potassium even against their concentration and thus this require energy.

36. The resting membrane potential varies from cell to cell. The range of the value lies between -20mV to -100mV. For example a typical neuron has -70mV and a muscle cell has -90.

37.

When chloride channel open, the more chloride ions move into the cell causing hyperpolarization.

When calcium channel open, calcium ion enters into the cell causing causing dpolarization.

When sodium channel open, more sodium ions diffuse out of the cell than potassium ions diffuse out of it causing hyperpolarization.

When potassium channel opens, potassium ions diffuse out of the cell causing hyperpolarization.

38. If the membrane potential is more negative it is less likely to fire because depolarization is necessary to generate an action potential. If the membrane potential is more positive it is more likely to fire.

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