http://www.the-scientist.com/?articles.view/articleNo/50208/title/Do-Microbes-Tr

Question

http://www.the-scientist.com/?articles.view/articleNo/50208/title/Do-Microbes-Trigger-Alzheimer-s-Disease-/

Read the attached article: Do microbes trigger Alzheimer's disease? Write no more than a 2-page summary of the article, focusing on the following questions:

1) What type of pathogen(s) seems to be the cause of Alzheimer's in the patients studied

2) Describe briefly the role of biofilms in immune responses

3) What lesions in the brain are present and indicative of Alzheimer's disease.

4) What process triggers neuronal death in the brain of Alzheimers patients?

Explanation / Answer

3) in Alzheimer's disease there is the accumulation of the beta amyloid protein in the regions of the brain which is the indication of the Alzheimer's disease..!!

1) Alzheimer's disease is not caused due to the pathogens.. It is due to gene expression where the more protein beta amyloid protein in the brain and due to the tau protein which results in the cell death of the neurons and results in breakout of communication between the cells Hence results in dementia.. No pathogens are involved in Alzheimer's disease..!!

4) the cells dies because of the tau protein.. More and more hyperphoshorylated tau proteins gets accumulated and combine together to head and tail fashion to form tangles which results in dissociation of microtibules of the cell resulting in the breaking of cell cytoskelton.. Hence results in death of the neuron cells...!!

3) Bioflim is the accumulation of the microbes on the cell surface. They are useful in activating both innate and adaptive immunity in the body.. They help the immune system to recognize the them strengthen them and activate them thus leading to phagocytosis. They can be helpful in production of memory cells for further attack can be used to promote faster immunity..!!

Related Questions

Navigate

• Browse (All)
• Browse H
• Subjects

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.