The gene for nail patella syndrome (N), a rare autosomal dominant trait, is 10 m

Question

The gene for nail patella syndrome (N), a rare autosomal dominant trait, is 10 map units apart from the gene (I) which determines the ABO blood group.

Greg and Susan each have nail patella syndrome.

Greg has blood type A, and Susan has blood type B.

What is the probability that their child will have normal nails and knees and will be blood type O?

(Gregs mother has nail patella syndrome and type A blood, and Gregs father has normal nails and knees and type O blood)

(Susans mother has nail patella syndrome and type O blood, and Susans father has normal nails and knees and type B blood.)

Explanation / Answer

Since, Gregs mother has nail patella syndrome and type A blood, and Gregs father has normal nails and knees and type O blood; so the genotype of Greg will be IAIONn.

Since, Susans mother has nail patella syndrome and type O blood, and Susans father has normal nails and knees and type B blood; so genotype of Susan will be IBIONn.

The probability that their child will have normal nails and knees and will be blood type O = 1/4 * 1/4 = 1/16

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