Exercise 16-4 Endocrine \"Mystery Cases\" n this exercise you will be playing th
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Exercise 16-4 Endocrine "Mystery Cases" n this exercise you will be playing the role of "endocrine detective" to solve endocrine discase mysteries. In each case you will have a victim who has saddenly fallen ill with a mystcrious malady. You will be presented a set of "witnesses, each of whom will give you a clue as to the nature of the illness. Other clues will come from samples you send off to the lab for analysis. You will solve the mystery by peoviding the victim a diagnosis. You may wish to use your textbook for assistance When you have completed the cases, answer Check Your Understanding question 7 (p. 444), Case 1: The Cold Colonel You are called upon to visit the ailing Col. Lemon. Before you see him, you speak with three witnesses who were with him when be fell ill Witness statements Ms. Magenta: "Col. Lemon has been hot-blooded for as long as Il've known him. But I noticed that he couldn't seem to keep warm. He kept complaining about being cold. Mr. Olive "Just berween you and me, I've noticed that the old chap has put on quite a bit of weight lately the energy to do much of anything ! Professor Purple: "The colonel and I used to go on major expeditions together. Now he just doesn't seem to have t are your initial thoughes about the witnesses' statements? Does one hormone come to mind that may be the cause? Explain. 16 the colonel and collect some blood to send off to the lab. The analysis comes back as follows (triodothyronine): 0.03 ng/dl (normal: 0.2-0.5 ng/dl) T4 (thyroxine): 1.1 /dl (normal: 4-7 Pg/dl) TSH (thyroid-stimulating hormone): 86 mUN (normal: 0.3-4.0 mLM) Analyze the results. Why do you think the T3 and T4 are low and the TSH is elevated? Based upon the witness statements and the laboratory analysis, what is your final diagnosis? Explain Col. Lemon's symptoms. Endocrine System UNIT 16 435Explanation / Answer
1. From Ms.Magenta : We could understand that Col.Lemon had Cold Intolerance , which is a prominent sign of Hypothyroidism.
2. Statement from Mr.Oliver : Reaffirms Hypothyroidism which has symptoms of Weight Gain.
3. Prof. Purple : Confirms that Col. had Fatigue,Weakness that he did not have energy for expeditions.
T3 & T4 Levels in the lower side , automatically elevates TSH levels since it always go in the opposite direction of the thyroid hormone.
If TSH is higher than 4.0 mU/L on repeat tests, he probably have Hypothyroidism,which is confirmatory with his Signs & Symptoms.
Hence Col.Lemon is suffering with Hypothyroidism.
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