table 8.2 extracellular intracellular fluid Eion K+ 5 mM 150 mM -90mV Na+ 145 mM
ID: 3508245 • Letter: T
Question
table 8.2
extracellular intracellular fluid Eion
K+ 5 mM 150 mM -90mV
Na+ 145 mM 15 mM +60 mV
Cl- 108mM 10mM -63mV
THIS IS THE ONLY INFO GIVEN
G) Now repeat your calculation for Vm just like in part D using Table 8.2 for your concentration values, however, this time substitute ONE value using the table on the left. For instance, the table to the left has ext K+ concn 50. Substitute the "50" for the "5" that is given by Table 8.2. You will have to do a total of 10 calculations. Fill in the table ext K+concn Vm ext Na+ cnn Vm 145 150 160 200 290 with your answers. [Again you are using the GHK equation 25 50 Looking at your data: 10) What happens to Vim as the Kv concentration goes higher? What would this do to neuronal activityExplanation / Answer
If the k+ concentration rises higher from 5 to 50 mM, then the Resting membrane potential within the neuronal cells are also elevated from - 70mV to a higher potential of more than -700mV.
This in turn increases the excitability of neurons in the central nervous system as well as the peripheral nervous system.
This results in sudden and intense episodes of seizures or severe tremor.
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