A hospital lab technician has determined that Shelley only has antigen Rh on her
ID: 3509693 • Letter: A
Question
A hospital lab technician has determined that Shelley only has antigen Rh on her red blood cells. Use this information to answer the questions: following 9. What is Shelley's blood type? 10. Make a list of the blood types that can be used as donor blood for Shelley 11. Shelley can donate her blood to what blood type(s)?Explain your answer 12. Make a list of the blood types that can be used as donor blood for Shelley in a whole blood transfusion. 13. Below make a sketch of what Shelly's blood type test results would look like. Rh 14.A woman with a blood type A- has two children; one has blood type A+ and one has blood type AB+. She gets pregnant a third time by a man with blood type B-. In theory, is the fetus in danger of developing hemolytic disease of the newborn? Explain why or why not 15.In practice, would this woman be treated to prevent hemolytic disease of the newborn? 16.Is this man above the father of the woman's fist two children? Explain why or why notExplanation / Answer
Although all blood is made of the same basic elements, not all blood is alike. In fact, there are eight different common blood types, which are determined by the presence or absence of certain antigens – substances that can trigger an immune response if they are foreign to the body. Since some antigens can trigger a patient's immune system to attack the transfused blood, safe blood transfusions depend on careful blood typing and cross-matching.
The ABO Blood Group System
There are four major blood groups determined by the presence or absence of two antigens – A and B – on the surface of red blood cells:
Group A – has only the A antigen on red cells (and B antibody in the plasma)
Group B – has only the B antigen on red cells (and A antibody in the plasma)
Group AB – has both A and B antigens on red cells (but neither A nor B antibody in the plasma)
Group O – has neither A nor B antigens on red cells (but both A and B antibody are in the plasma)
Answers:
9. As per the below picture shellys blood type is AB +(Rh factor was considered from the first paragraph).
10. A,B,AB, O (universal recipient)
11. Only to AB + blood group persons:
Rationale behind this is AB blood group people had only antigen but had abscence of antibodies in their plasma of blood for instance if blood is transfered to A, B or O immediately reaction happend and blood gets clumps; so blood grouping and matching test plays a vital role in blood transfusion.
12. AB positive.
13. AB positive.
14. Hemolytic disorder of new borm baby:HDNB
Hemolytic disease of the newborn, also known as hemolytic disease of the fetus and newborn, HDN, HDFN, or erythroblastosis fetalis is an alloimmune condition that develops in a fetus, when the IgG molecules (one of the five main types of antibodies) produced by the mother pass through the placenta. Among these antibodies are some which attack antigens on the red blood cells in the fetal circulation, breaking down and destroying the cells (hemolysis). The fetus can develop reticulocytosis and anemia. This fetal disease ranges from mild to very severe, and fetal death from heart failure (hydrops fetalis) can occur.
Answer: Mother might develop antibodies of A, and B so in the third birth even if she concieved with man grouping to A- blood there is a change of HDNB.
15. Aboslutely';she should be treated with IVIG - IVIG which had been used to successfully treat many cases of HDN. It has been used not only on anti-D, but on anti-E as well (IVIG: Intravenous immunoglobulin)
16. The fathers blood group in the above instance is AB +
Reason: In first time moher got A+ and in second AB + so if father is B A cannot be obtained and if he is A AB cannot be obtained so the only possible grioup is AB +; regarding the rheusus factor he is positive because second child is AB +
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