Later his blood tests revealed that there was cardiac troponin in his blood, con
ID: 3511340 • Letter: L
Question
Later his blood tests revealed that there was cardiac troponin in his blood, confirming the doctor’s diagnosis.
10. Why do victims of a heart attack have cardiac troponin in their blood? (1 pt)
The doctor explained to Joe’s wife that plaque in his arteries had ruptured causing a blood clot to form. The clot was dislodged due to his high blood pressure and got stuck in a coronary artery, which normally delivers oxygen-rich blood to his cardiac muscle.
11. If a coronary artery becomes blocked, blood flow to the heart is reduced. a) How does lack of blood flow affect oxidative metabolism?
b) What will happen to the pH of the affected heart cells?
c) What will happen to levels of ATP in the affected heart cells?
d) What will happen to calcium levels in the cytosol of the affected heart cells and why?
e) What will happen to the gap junctions between the affected heart cells and other cells?
f) What will happen to the conduction of electrical signals across the affected tissue?
Explanation / Answer
1.cardiax troponin T and I are specific to cardiac muscle.
Increasevin cardiomyocyte stretch and memebrane permeability can lead to troponi release from cytosolic pool.
Increas wall stress lead vto cardiomyocyte apoptosis,autophagy and breakdown of contractile apparatus releasing cardiac troponin.
10 a.decrease ib blood flow lead to decrease in oxygenation and that impede kreb 's cycle and overall decrease in energy i,e,decreasevin ATP.that impede aerobic metabolism so there will be anaerobic metabolisn and accumulation of lactic acid.
B.pH of cell decrease due to accumulation of lactic acid.
C.there is decrease in atp level due to anaerobic metabolism
Related Questions
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.