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1) During IGV heavy recombination the processes that can\'t you be at additional

ID: 3513008 • Letter: 1

Question

1) During IGV heavy recombination the processes that can't you be at additional diversity at the third complementary determining region of IG variable regions include

2) A positive feedback loop established between Macrophages and Dendritic cells in infected tissue's involves the secretion of_______ by the Macrophage and ______ by that NK cells.

3) What time is used to refer to the strength of the interaction between a single action binding site of an antibody and a corresponding Ligand?

4) Which of these is a transcription factor involved in signal transduction?

5) Considering only combinatorial joining of genes light and heavy changes how many different anti-body molecules potential he could be generated from germline DNA containing 500 V light and 4J light gene segments and 300 V heavy 15 D heavy and 4J have the gene segments 6) What controls the v heavy joining and D heavy but not J have the gene segments?

Explanation / Answer

ANS 1) The third CDR complementary determining region of IG variable is the most variable one and these regions include: some of V regions, all of D overwhelming chains and joining J regions.

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ANS 2) A positive feedback loop established between Macrophages and Dendritic cells in infected tissue's involves the secretion of IL-12 (INTERLEUKIN 12)  by the Macrophage and IFN-y (INTERFERON GAMMA) by that NK cells.

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ANS 3) SPECIFICITY is used to refer to the strength of the interaction between a single action binding site of an antibody and a corresponding Ligand.

The capacity of an individual counter acting agent joining site to respond with just a single antigenic determinant is the specificity time of the reactions. A solid antigen-counter acting agent connection requires high level of specificity.

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ANS 4) AP-1 and CREB/ATF proteins transcription factors are involved in signal transduction

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