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1) During exercise, skeletal muscle glycogenolysis can be activated by all of th

ID: 913396 • Letter: 1

Question

1) During exercise, skeletal muscle glycogenolysis can be activated by all of the following EXCEPT:

a) insulin mediated increase in phosphatase activity

b) epinephrine mediated increase in cAMP

c) Epinephrine independent release of Ca+2

d) allosteric activation of glycogen phosphorylase by AMP

2) A 5-year old girl displayed increased appetite, urinary frequency, and thirst. Her physician suspected new onset diabetes mellitus and confirmed that she had elevated urine glucose and ketones. If this individual were to have an episode of diabetic ketoacidosis, you would expect her blood gas analysis to show which of the following characteristics consistent with respiratory compensation during this event?

a) increased blood pH

b) decreased blood Ph

c) decreased blood glucose

d) decreased ketone synthesis

Explanation / Answer

During exercise, skeletal muscle glycogenolysis can be activated by all of the following EXCEPT:

a) insulin mediated increase in phosphatase activity

Because the control of glycogenolysis occurs via neutral - muscle activation (Ca+2), endocrine (catecholamine, cyclic-AMP), and metabolic (AMP, G-6-P, IMP, Pi and pH) mechanisms.

2). b) decreased blood Ph is expected her blood gas analysis to show with respiratory compensation during this event.