2. What is the role of the SRY gene? 3. Why is anti-mullerian hormone (AMH) nece

Question

2. What is the role of the SRY gene? 3. Why is anti-mullerian hormone (AMH) necessary for development of the male internal reproductive organs? 4. What are the genetic (chromosomal) factors that can produce sexual variations, e.g. identify the cause and characteristics of Turner's syndrome. . What are the hormonal factors that can produce sexual variations, e.g. identify the cause and characteristics of CAH (congential adrenal hyperplasia), AIS (androgen insensitivity syndrome), and lack of 5-alpha-reductase (DHT-deficiency syndrome) 6. Describe the CAH evidence showing the prenatal effect of 7. What are the possible genetic influences on sexual orientation? 8. What are the possible hormonal influences on sexual androgens on the human brain Describe the evidence supporting genetic influences. orientation? Describe the evidence supporting hormonal influences. 9. Describe how fraternal birth order effect might influence sexual orientation

Explanation / Answer

2. The SRY gene is found on the Y chromosome. It initiates the male embryonic development in the XY sex determination system. It also leads to the development of male phenotypes. SRY gene does this by providing instructions for making a protein known as sex- determining region Y protein. This acts as a transcription factor, it binds to specific regions of DNA and helps in controlling the activity of certain genes. It essentially starts the process of development of male reproductive organ as in testes and prevent the development of female reproductive organ such as fallopian tubes, uterus.

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