a)You have decided to ascend to the summit of Mount Everest where the partial pr
ID: 3517275 • Letter: A
Question
a)You have decided to ascend to the summit of Mount Everest where the partial pressure of oxygen in the atmosphere has been estimated to be about 54 mmHg. Recall that when this air arrives in the alveoli, the partial pressure of oxygen drops even further than this because of displacement by the partial pressure of carbon dioxide and water vapor. The arterial concentration of oxygen at the pulmonary capillaries is measured and found to be 25 mmHg.?How would the hemoglobin saturation curve shift in this situation? Would this help ensure that the body’s tissues get the oxygen it needs and if so, how?
b)If you were to genetically alter the production of 2,3-DPG in the systemic capillaries, what would you do to make your situation on Mount Everest better? Explain your answer.
Explanation / Answer
a) Heamoglobin curve shifted towards right in this situation due to lower pO2 of 25mmHg at mountain everest , Yes this condition allows the body to produce more and more erytropoetin cell from kidney to carry maximum oxygen to meet the need in this situation.
b) 2,3 -DPG produce due to the side shunt reaction in glycolysis and this a very anionic phosphate which causes release of oxygen from hemoglobin and hemoglobin curve shifted towards right.
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