35 For each of following statements, indicate for which coated vesicle the state

Question

35 For each of following statements, indicate for which coated vesicle the statement is true: clathrine-, COPI-, or COPII- Each statement may be true for one, several or none of the coated vesicles discussed above. a) Fusion of the vesicle (after dissociation of coat) with the Gologi membrane is facilitated by specificlated by specific t-SNARE and Rab proteins( b) Has a role in sorting proteins for intracellular transport between ER and Goligi c) Is essential for endocytic progress d) Is important for retrograde traffic through the Golgi apparatus

Explanation / Answer

a) COPI, COPII [COPI, COPII, Clathrin all are coat protein for coating vesicles. Rab protein and t-SNARE both are essential for membrane fusion, the v-SNARE on vesicle membrane and t-SNARE on target membrane forms 4 alpha helix for membrane-membrane fusion. So this protein is needed for both COPI and COPII. After dissociation of coating mean dissociation of clathrin after endocytosis ]

b) COPI, COPII [The COPI and COPII act in the intracellular interface ER-GOLGI or GOLGI-GOLGI interface, while Clathrin is involved in endocytosis. So COPI, COPII are intracellular sorting proteins which decide which will go to ER and which will go to GOLGI, Clathrin works at the extra and intracellular process.]

c.) Clathrin

d) COPI ( COPI works at retrograde and anterograde both way but COPII in anterograde manner)

Related Questions

Navigate

• Browse (All)
• Browse 3
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.