Apart from suffering from recurrent and prolonged infections, Marie Curie also e

Question

Apart from suffering from recurrent and prolonged infections, Marie Curie also experienced the following signs and symptoms: fatigue, rapid heart rate, pale skin, easy bruising, prolonged bleeding from cuts, and dizziness. Bone marrow transplant was not an option at that time and so blood transfusion was the treatment of choice. Explain the reasoning behind these other signs and symptoms that Curie experienced. Assume her blood group was A negative. Which blood groups can she receive? Which blood groups can she not receive? Explain why. Be detailed in your explanation and support your answer with facts from your textbook, research, and articles from scholarly journals. In addition, remember to add references in APA format to your posts to avoid plagiarism.

Explanation / Answer

Answer. Marie Curie was also known as Madam Curie. She has received Nobel Prize in Physics for her discovery of Radioactivity with her husband.

Exposure to the radiations caused APLASTIC ANAEMIA, in her. All the signs and symptoms given in the question relates to her illness. In this disease, basically the mature blood cells (RBC, WBC and platelets) are not formed in the bone marrow due to defect in the bone marrow stem cells.

Blood group A- means she is having A antigen on the RBC surface and anti-B antibodies in the plasma. Negative here signifies the absence of the Rh factor. Thus, she can have blood transfusion from the A- & O- individuals. As O blood group is not having any antigen on their red blood cells, thus it will not cause aggulitination reaction. She is Rh negative thus this negativity should also match,that's why she can have blood group from O- & A- donors.

She cannot have blood from O+, AB+, AB-, B+ & B-. Because presence of B antigens in blood group AB And B will cause aggulitination reaction in her. O+ contains Rh factor but she is Rh factor negative thus she cannot have blood from a positive donor.

References:

Dean, L. (2005) Blood Groups and Red Cells Antigens. Bethesda, US: National Center for Biotechnology Information.

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