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List the organs and structures of the digestive system that function in enzymati

ID: 3520383 • Letter: L

Question

List the organs and structures of the digestive system that function in enzymatic hydrolysis. For the following enzymes used in enzymatic hydrolysis, discuss the activation, where applicable, list the substrates and products, and discuss the mechanisms used to regulate secretion and/or activation of each enzyme: trypsin, chymotrypsin, carboxypeptidase, dipeditdase, deoxyribonuclease, ribonuclease

Explanation / Answer

Enzyme Organ Activation Substrate Product Mechanism of regulation/activation Trypsin Secreted from acinar cells of pancreas and acts in the small intestine ( mainly duodenum) Secreted as zymogen granules ( trypsinogen). The enteropeptidase from intestinal mucosa activates it to trypsin Proteins Peptides + Amino acids Fat, proteins in the intestine secrets Cholecystokinin-> increase pancreatic secretion Chymotrypsin Secreted by pancreatic cell, acts in the small intestine Secreted as chymotrypsinogen and Activated by trypsin Polypeptides Peptide fragments, Same as above. Carboxypeptidase Secreted by Pancreas act in the small intestine Some carboxypeptidase secreted as a zymogen and activated by trypsin Polypeptide Smaller polypetides+ amino acids Dipeptidase Secreted by enterocytes of small intestine-> acts in the small intestine Dipeptides Amino acids Deoxyribonuclease available throughout the body system-> catalyzes the hydrolysis of DNA (PHOSPHODIESTER LINKAGE) DNA Nucleotides Ribonuclease Available throughout the body. RNA Nucleotides

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