R.J. is a 15-year-old boy with a history of asthma diagnosed at age 8. His asthm
ID: 3520443 • Letter: R
Question
R.J. is a 15-year-old boy with a history of asthma diagnosed at age 8. His asthma episodes are triggered by exposure to cats and various plant pollens. He has been using his albuterol inhaler 10 to 12 times per day over the last 3 days and is continuing to wheeze. He normally needs his inhaler only occasionally (2 or 3 times per week). He takes no other medications and has no other known medical conditions. Physical examination reveals moderate respiratory distress with a respiratory rate of 32, oximetry 90%, peak expiratory flow rate (PEFR) 60% of predicted, and expiratory wheezing. Question 1. In addition to bronchodilator therapy with intermittent albuterol, what other pharmacotherapy is important in the management of asthma?
A. Inhaled corticosteroids are effective in reducing inflammation by stabilizing mast cell membranes and blocking mast cell migration and leukocyte chemotaxis, and are used for prophylaxis.
B. Leukotriene blockers are used to reduce bronchodilation.
C. Pharmacotherapy is aimed at reducing bronchodilation..
D.Short acting ß2 agonists may be used for acute attacks of bronchial smooth muscle dilation. Longer acting agents are used for routine maintenance.
Explanation / Answer
The Answer is A. Inhaled corticosteroids are effective in reducing inflammation by stabilizing mast cell migration and leukocytes chemotaxis, and are used for prophylaxis .
Additional information:
Despite corticosteroids, anti inflammatory agents, mast cell blocker, leutokrine modifier also can be given.
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