I need help putting these steps in order: The steps for the mechanism of action

Question

I need help putting these steps in order: The steps for the mechanism of action of G protein-linked receptors from the time a neurotransmitter binds the receptor to the generation of a physiological response are:
The G protein binds to an effector protein.
A second messenger is generated.
GTP binds to and activates a G protein.
Gene transcription is activated in the nucleus.
Thank you! I need help putting these steps in order: The steps for the mechanism of action of G protein-linked receptors from the time a neurotransmitter binds the receptor to the generation of a physiological response are:
The G protein binds to an effector protein.
A second messenger is generated.
GTP binds to and activates a G protein.
Gene transcription is activated in the nucleus.
Thank you! The steps for the mechanism of action of G protein-linked receptors from the time a neurotransmitter binds the receptor to the generation of a physiological response are:
The G protein binds to an effector protein.
A second messenger is generated.
GTP binds to and activates a G protein.
Gene transcription is activated in the nucleus. A second messenger is generated.
GTP binds to and activates a G protein.
Gene transcription is activated in the nucleus.
Thank you!

Explanation / Answer

Answer.

The correct order is-

After this step, GTP hydrolysis occurs and GPCR regains its normal shape as its alpha subunit binds to it again to carry on another cycle. Cell signaling using GPCR is a cycle that repeats over and over in response to the signal binding.

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