In celiac disease, the body starts to secrete antigluten and antigliadin antibod

Question

In celiac disease, the body starts to secrete antigluten and antigliadin antibodies. Research has

shown that can lead to changes in the brain (e.g., cerebellar atrophy and cerebral calcification). Why might this occur?

a) The antigluten and anti gliadin antibodies begin to attack the cells in these brain areas.

b) The cells in these brain areas can respond to antigluten and antigliadin antibodies.

c) The cells in these brain areas can secrete antigluten and antigliadin antibodies.

d) The cells in these brain areas have cell surface proteins that are similar in structure to gluten and gliadin.

Explanation / Answer

Answer : option D) The cell in these brain areas have cell surface proteins that are similar in structure to gluten and Gliadin.

Reason : in coeliac disease our bodies immune system start producing antibodies against gluten food products so now this antibodies surely are programmed to attack intestinal cells but cells present in brain they mimics or better to say they present as cells similar to gluten receptor in brain so now what happens is the antibodies which where programmed to attack intestinal cells and attack brain cells as they unable to distinguish this causes coeliac disease

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