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Autosomal Dominant Compelling Helioophthalmic Outburst Sydrome (ACHOO Syndrome:

ID: 35237 • Letter: A

Question

Autosomal Dominant Compelling Helioophthalmic Outburst Sydrome (ACHOO Syndrome: sneezing in response to bright light) and Geniospasm (Trembling Chin, triggered by anxiety) both appear to be dominant traits in humans. Part A What is the probability that the first child of parents who are heterozygous for both the achoo and trembling chin alleles will have achoo syndrome but lack the trembling chin? Enter your answer as a fraction. B.What is the probability that the first child of parents who are heterozygous for both the achoo and trembling chin alleles will not have achoo syndrome or trembling chin?

Explanation / Answer

at f1 generatiobn all the ofsprings will be heterozygous

Aa Tt X Aa Tt -----------------------   3/4 A (achoo) , 1/4 (nonachoo) , 3/4 T(ntrembling) , 1/ 4 non trembling

the probability of a child with achoo and without trembling would be 3/4 A x 1/4 tt = 3/16

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