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A) Intermediate filaments B) Microtubules C) Microfilaments D) Actin filaments E

ID: 36705 • Letter: A

Question

A) Intermediate filaments B) Microtubules C) Microfilaments D) Actin filaments E) Keratin-associated filaments

A) cytokeratins-epithelial B) desmin-smooth muscle

C) vimentin-mesenchymal D) nestin-connective E) GFA protein-nervous

________ resist tensile forces and contain keratin to form the protective barrier of the skin.

A) are composed of four linear strands.

B) are composed of polymerized G-actin monomers wound around each other in a helix.

C) are oriented similar to DNA, with strands helical and antiparallel to one another.

D) are composed of G-actin dimers.

E) polymerize at the same rate in both directions from both ends of the filament.

Which of the following intermediate filament proteins is incorrectly matched with the tissue in which it is found?

A) vincristine; bacterial infections B) vinblastine; antidpressent

C) taxol; breast cancer D) nocodazole; allergies E) benzimidazole; hypertension treatment

F-actin filaments

A) serves as a site for microtubule and microfilament assembly.

B) acts as an anchor for both ends of the microtubule.

C) is associated with two centrioles in plant cells.

D) is called a centrosome during interphase.

E) is positioned near the cell membrane

One of the following drugs blocks cell division because it stabilizes the microtubules. What is this drug, and for what is it used?

A) mitotic spindle formation.B) muscle cell contraction.C) amoeboid movement.D) cytoplasmic streaming.E) cell migration.

The microtubule-organizing center (MTOC)

A) cause microtubules to lengthen.

B) destabilize microtubules.

C) stabilize microtubules.

D) cause microtubules branching.

E) connect microtubules to microfilaments.

All of the following are roles of microfilaments except

A) ?-tubulin; cilium

B) ?-tubulin; ?-tubulin

C) ?-tubulin; tubulin GTP D) ?-tubulin; pericentrin E) ?-tubulin; tubulin GTP

Capping proteins such as CapZ

A) Tau B) stathmin/Op18 C) kinesin D) catastrophins E) MAP 2

Ring-shaped complexes in the centrosome contain ________ in combination with ________.

A) Dynein B) Actin C) Tau D) Kinesis E) Tubulin

Which of the following proteins is associated with the precise control of where microtubules form and depolymerize?

A) are highly disorganized and very unstable.

B) may be loosely associated with basal bodies.

C) are organized around a central shaft or axoneme.

D) are required to maintain axons.

E) all of the above

  

________ causes microtubules to form tight bundles in nerve cells.

A) centriole B) centrosome C) plasma membrane D) centromere E) mitochondrial outer membrane

Axonemal microtubules The minus (-) ends of microtubules are often anchored at the ________________ , such that the dynamics associated with microtubules is at the plus (+) ends. dynamic instability. B) treadmilling. C) microtubule organizing. D) MAP motoring. E) actin-regulated assembly.

A) addition of tubulin subunits to (

Explanation / Answer

Activation of which of the following is associated with the formation of focal adhesions and stress fibers?

A) Rho kinase.

2. Which of the following drugs disrupt microtubules and can used for chemotherapy?

B) vincristine

3. Rho GTPases have the all of the following effects on cytoskeletal actin except

.B) formation of pseudopodia.

4. Which of the following about the current model of muscle contraction is correct ?

actin and myosin have the same molecular weight.

Which of the following major protein components of skeletal muscle is incorrectly matched with its function?

A) titin-links thick Z bands

All of the following are moved by molecular motors except

D) glucose.

Striated muscle has light and dark bands. The light bands are called ________, whereas the dark bands are called ________.

A) Z lines; M lines

In relaxed muscle, calcium is found in high concentration in the

C) sacroplasmic reticulum. SR

All of the following are actin-dependent nonmuscle motility except

C) chemotaxis.

Calcium-calmodulin complexes ultimately mediate the phosphorylation of myosin in which of the following cells?

A) smooth muscle B) cardiac muscle

C) neurons D) pacemaker E) skeletal muscle

In addition to microtubule motor proteins, ________ are also involved in vesicular transport.

E) Dyenin

The calcium pump or calcium ATPase in skeletal muscles

A) is responsible for removing calcium from the T tubule.

Muscle contraction occurs in a cyclic process. Which of the following sequences is in the correct order?

A) power stroke, cross bridge formation, cross bridge dissociation, cocking of myosin

Which of the following process(es) requires energy in the form of ATP hydrolysis ?

E) all of the above

Dyneins are

B) associated with cilia and flagella.

Which of the following is associated with retrograde movement in fast axonal transport?

A) dynein

Kinesin is a motor molecule that is characterized by

) motion toward the "plus" end of the microtubule.

All of the following are examples of nonmuscle motility and contractility except

A) microsome formation.

You wish to inhibit the contraction of muscle in vitro as a control for an experiment you are conducting. To do this, which of the following would you use?

A) colchicine

A calcium-binding protein that aids in the activation of many enzymes, including myosin light-chain kinase, is

C) calmodulin.

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