Calculate the inulin concentration during antidiuresis in the following location

Question

Calculate the inulin concentration during antidiuresis in the following locations. Calculate the inulin concentration during antidiuresis in the following locations. Plasma (inulin] is maintained at 12.2 mg/dL. Calculate the inulin concentration during antidiuresis in the following locations A(5 Points) At the end of the proximal tubule, Q = 37 mL/min. B (5 Points) At the end of the thick ascending limb/early distal tubule Q = 19 mL/min. C (5 Points) At the late distal tubule. Q=5 mL/min. D (5 Points) In the final urine. Q=0.78 mL/min.

Explanation / Answer

Concentration of inulin in urine = Urine flow rate / Plasma concentration of inulin

Plasma concentration of inulin = 12.2 mg/dl = 12.2 mg/ 100 ml = 12.2 x 10-2 ml

A. Concentration of inulin at the end of proximal tubule = 37 / 12.2 x 10-2 = 303.2 mg/ml

B. Concentration of inulin at the end of thick ascending limb / early distal tubule = 19 / 12.2 x 10-2 = 155.73 mg/ml

C. Concentration of inulin at late distal tubule = 5 / 12.2 x 10-2 = 40.98 mg/ml

D. Concentration of inulin in final urine = 0.78 / 12.2 x 10-2 = 6.39 mg/ml

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