QUESTION 21 Choose the INCORRECT statement regarding Toll-like receptors (TLRs).

Question

QUESTION 21

Choose the INCORRECT statement regarding Toll-like receptors (TLRs).

When TLRs bind to microbes, they trigger activation of NFkB

The binding of TLRs to a microbe triggers phagocytosis of the microbe

TLRs bind to pathogen-associated molecular patterns (PAMPs) such as LPS

The binding of TLRs to microbes can lead to expression of the gene encoding iNO

When TLRs bind to microbes, they trigger activation of NFkB

The binding of TLRs to a microbe triggers phagocytosis of the microbe

TLRs bind to pathogen-associated molecular patterns (PAMPs) such as LPS

The binding of TLRs to microbes can lead to expression of the gene encoding iNO

Explanation / Answer

The toll - like receptors (TLRs) when bind to microbes they first elicit the cytokines responsible for causing inflammation, then the antigens are presented to CD4+ cells and TLRs also produce viral infecting interferons. Therefore, the statement 'When TLRs bind to microbes, they trigger activation of NFkB' is incorrect.

Option A is correct.

Related Questions

Navigate

• Browse (All)
• Browse Q
• Subjects

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.