1) Suppose you increased the rate at which eukaryotes can remove ribonucleotides

Question

1) Suppose you increased the rate at which eukaryotes can remove ribonucleotides from their DNA. How would this affect the fidelity of replication and why?
2) suppose that you increased the concentration of lac repressor in E. coli by 50-fold. How would this impact the expression of the genes encoded by the lac operon in the presence and absence of Lactose and why? 1) Suppose you increased the rate at which eukaryotes can remove ribonucleotides from their DNA. How would this affect the fidelity of replication and why?
2) suppose that you increased the concentration of lac repressor in E. coli by 50-fold. How would this impact the expression of the genes encoded by the lac operon in the presence and absence of Lactose and why?
2) suppose that you increased the concentration of lac repressor in E. coli by 50-fold. How would this impact the expression of the genes encoded by the lac operon in the presence and absence of Lactose and why?

Explanation / Answer

(1) The enzymes RNase H2 and RAD14 or flap endonuclease FEN1 can do the job. Increasing the speed can reduce the replication time and efficiency of removal

Ribonucleotides are integrated in the DNA during replication or repair, but as ribose is a significantly more unstable molecule compared to deoxyribose due to its 2

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