Molecular Genetics Help Needed! 1) LOD scores: a) are always positive b) can ass

Question

Molecular Genetics Help Needed!

1) LOD scores:

a) are always positive

b) can assume any value

c) are always between 0 and 1

d) are always between -1 and 1

2) In the figure below: he maximal LOD score for linkage of locus A to the disease will occur at what value of theta (what expected recombination fraction)?:

a) 0

b) 1/6

c) 1/5

d) 1/4

e) 1/2

3) In the figure below: one individual in the third generation is recombinant for paternal alleles at the loci A and B. Which one?

a) III-1

b) III-2

c) III-3

d) III-4

e) III-5

Molecular Genetics Help Needed! 1) LOD scores: a) are always positive b) can assume any value c) are always between 0 and 1 d) are always between -1 and 1 2) In the figure below: he maximal LOD score for linkage of locus A to the disease will occur at what value of theta (what expected recombination fraction)?: a) 0 b) 1/6 c) 1/5 d) 1/4 e) 1/2 3) In the figure below: one individual in the third generation is recombinant for paternal alleles at the loci A and B. Which one? a) III-1 b) III-2 c) III-3 d) III-4 e) III-5

Explanation / Answer

1.b) can assume any value

2.1/5.The LOD score compares the likelihood of obtaining the test data if the two loci are indeed linked,Positive LOD scores favor the presence of linkage, whereas negative LOD scores indicate that linkage is less likely.

3. b

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