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1) The first 15 bases of thecoding region of a gene are shown below. The sequenc

ID: 4647 • Letter: 1

Question

1)      The first 15 bases of thecoding region of a gene are shown below. The sequence is from thenon-template (or coding) strand. The first codon is methionine. Foreach of the following mutations of this sequence, indicate whetherthe mutation is a transition, transversion, insertion, or deletion.Also indicate whether it is a silent, missense, nonsense, orframeshift mutation.

5’ ATGGGACTAGATACC   3’

a.      5’ ATGGGTCTAGATACC   3’

b.     5’ ATGCGACTAGATACC   3’

c.      5’ ATGGGACTAGTTACC   3’

d.     5’ ATGTGACTAGATACC   3’

e.      5’ ATGGGCTAGTTACC   3’

Explanation / Answer

5’ ATGGGACTAGATACC   3’

The second sequence is:

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