dinitrophenol (DNP) is a compound that shuttles protons across membranes, abroga

Question

dinitrophenol (DNP) is a compound that shuttles protons across membranes, abrogating any proton motive force (PMF). How will this affect ATP synthesis via ATP synthase? How will this affect ATP synthesis via fermentation? Assume excess of all coenzymes.

Question 3 options:

ATP synthetase will stop functioning because there is no PMF. Fermentation reactions will continue because substrate level phosphorylation occurs independently of the PMF.

ATP synthetase will still function because it is works independently of the PMF. Fermentation reactions will continue because substrate level phosphorylation occurs independently of the PMF.

ATP synthetase will still function because it is works independently of the PMF. Fermentation reactions will also stop because they require a proton motive force.

ATP synthetase will stop functioning because there is no PMF. Fermentation reactions will stop because they also require a proton motive force.

ATP synthetase will stop functioning because there is no PMF. Fermentation reactions will continue because substrate level phosphorylation occurs independently of the PMF.

ATP synthetase will still function because it is works independently of the PMF. Fermentation reactions will continue because substrate level phosphorylation occurs independently of the PMF.

ATP synthetase will still function because it is works independently of the PMF. Fermentation reactions will also stop because they require a proton motive force.

ATP synthetase will stop functioning because there is no PMF. Fermentation reactions will stop because they also require a proton motive force.

Explanation / Answer

ATP synthetase will stop functioning because there is no PMF. Fermentation reactions will continue because substrate level phosphorylation occurs independently of the PMF.

Hence, the correct option is (A).

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