The death rate per 100,000 for lung cancer is 7 among non-smokers and 71 among s

Question

The death rate per 100,000 for lung cancer is 7 among non-smokers and 71 among smokers. The death rate per 100,000 for coronary thrombosis is 422 among non-smokers and 599 among smokers. The prevalence of smoking in the population is 55%. The population etiologic fraction of disease due to smoking is:

0.80 for lung cancer and 0.28 for coronary thrombosis.

0.80 for lung cancer and 0.18 for coronary thrombosis.

0.83 for lung cancer and 0.28 for coronary thrombosis.

0.83 for lung cancer and 0.18 for coronary thrombosis.

cannot be determined from the information provided.

0.80 for lung cancer and 0.28 for coronary thrombosis.

0.80 for lung cancer and 0.18 for coronary thrombosis.

0.83 for lung cancer and 0.28 for coronary thrombosis.

0.83 for lung cancer and 0.18 for coronary thrombosis.

cannot be determined from the information provided.

Explanation / Answer

C. 0.83 for lung cancer and 0.18 for coronary thrombosis.

Given that The death rate per 100,000 for lung cancer is 7 among non-smokers and 71 among smokers. Then the relative risk (RR) of getting lung cancer = 71/7 = 10.1

The prevalence of smoking in the population is 55%. So, the population etiological factor of lung cancer (PEF) = 0.55(10.1 -1) /0`.55(10,1 -1)+1 = 0.83

The death rate per 100,000 for coronary thrombosis is 422 among non-smokers and 599 among smokers. The relative risk (RR) of getting coronary thrombosis = 599/422 = 1.42

The prevalence of smoking in the population is 55%. So, population etiological factor of coronary thrombosis (PEF) = 0.55(1.42 -1) /0`.55(1.42 -1)+1 = 0.18.

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