The death cap mushroom, Amanita phalloidins, contains several dangerous substanc

Question

The death cap mushroom, Amanita phalloidins, contains several dangerous substances, including the lethal amanitin. This toxin blocks RNA elongation in consumers of the mushroom by binding to eukaryotic RNA polymerase II with very high affinity; it is deadly in concentrations as low as 10^8 M. The initial reaction to ingestion of the mushroom is gastrointestinal distress (caused by some of the other toxins). These symptoms disappear, but about 48 hours later, the mushroom-eater dies, usually from liver dysfunction. Speculate on why it takes this long for amanitin to kill.

Explanation / Answer

Reason :

Duringthe elongation step in Transcription,the transcription complex consisting of RNA polymerase plus various elongation factors moves along the double stranded DNA copying the template strand to produce a single stranded RNA .

In the ex : shown below the RNA product is mRNA and enzyme would be RNA polymerase 2 in eukaryotes.

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