Which of the following statements regarding the reversible binding of ligands to
ID: 493165 • Letter: W
Question
Which of the following statements regarding the reversible binding of ligands to proteins is not true? Proteins generally bind only specific ligands. Sometimes, ligand binding causes conformational change of the protein. In proteins composed of multiple subunits, the conformational change in one subunit can lead to conformational change in other subunits. Protein-ligand interaction can be regulated by a third molecule. Proteins which have a large number of alpha helices are easier to regulate than those composed mainly of beta sheets. Which of the following proteins is used for oxygen storage? myoglobin ferritin hemoglobin antibody chymotrypsin Which of the following proteins is an enzyme? serotonin transporter cytokines actin chymotrypsin None of the above. Which force does nature use to hold a protein and its ligand together? hydrogen bond interaction electrostatic interaction hydrophobic interaction van der Waals interaction All of the above.Explanation / Answer
1. Protein - ligand binding can be both specific as well as non specific and hence D is wrong statmet and not true as protein ligand interacion only depends on concentration of ligand and structure of protein
proten-ligand interaction depends on concentration of ligand, structure of protein etc
2. Myoglobin is protein which stores oxygen in the muscle
answer is a
3. Chymotripsin is a digestive enzyme secreted by pancrease which acts on protein in deodenum
answer is D
4. Answer E all of the above
ligan can bnd to protein by using hydrogen bonding, electrostatic interaction, hydrophobic interaction and van der walls interaction
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