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1.Assume that you could “see” nicotinic acetylcholine receptors within the muscu

ID: 49994 • Letter: 1

Question

1.Assume that you could “see” nicotinic acetylcholine receptors within the musculature. How would they be arranged spatially?

a. evenly distributed on the cell’s surface like voltage-gated Na+ and K+ channels

b. in dense arrays within the motor end plate

2.   Assume that you could “see” neurosecretion from -motor neurons within the musculature of an animal standing still. What would this “look” like?

a. uniform, baseline secretion throughout the musculature

b. enhanced acetylcholine secretion within antigravity muscles, baseline secretion elsewhere

Explanation / Answer

1. b. in dense arrays within the motor end plate

The skeletal muscles are innervated by the parasympathetic nervous system and ACh is the neurotransmitter that act through the nicotinic type of receptors in skeletal muscles. Nicotinic acetylcholine receptors are densely localized in the motor end plates.

2. b. enhanced acetylcholine secretion within antigravity muscles, baseline secretion elsewhere

Gravitational forces on muscles induce asynchronous discharge in mono- and polysynaptic pathways and it sums in the alpha-motoneuron, which in coordination with CNS balances body posture.

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