In the last step of beta-oxidation of an odd numbered fatty acyl CoA, propionyl

Question

In the last step of beta-oxidation of an odd numbered fatty acyl CoA, propionyl CoA is produced.

What could this propionyl-CoA be used for in metabolism?

A. Propionyl CoA has no metabolic use; it will simply be secreted since it cannot directly enter the citric acid cycle.

B. Propionyl CoA, after several steps, including steps in the citric acid cycle, gives rise to a compound that could enter gluconeogenesis.

C. Propionyl CoA could enter glycolysis.

D. Propionyl CoA could be reduced in size by 1 C atom and then enter citric acid cycle as acetylCoA.

Explanation / Answer

propionyl co A is the end product of fatty acid metabolism of odd chain fatty acids and also a metabolite of branched chain fatty acids ,it act as a gulcose precursor through the gluconeo geneisis process {production of glucose from non carbohydrate source} .

so option B is correct ,propionyl coa ,after several steps ,including stps in tyhe citric acid cycle ,gives rise to a compound that could enter gluconeogenesis process

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