When a cardiac muscle cell contracts, neighboring cells attached to it soon also

Question

When a cardiac muscle cell contracts, neighboring cells attached to it soon also contract, followed shortly by yet more cardiac cells contracting. What is the basis for such sequential contraction?

When one cell contracts, the hydrostatic pressure inside the cell increases and liquid is forced into neighboring cells, causing them to contract in turn

Muscle contraction results in CO2 production. Excess CO2 diffuses to neighboring cells, causing them to contract

Positively charged ions enter a cardiac cell, causing more positive ions to enter. The excess ion charge travels through small channels to neighboring cells, causing them to contract

Contraction of one cell causes its neighbors to be stretched. Stretched cardiac cells contract

When one cell contracts, the hydrostatic pressure inside the cell increases and liquid is forced into neighboring cells, causing them to contract in turn

Muscle contraction results in CO2 production. Excess CO2 diffuses to neighboring cells, causing them to contract

Positively charged ions enter a cardiac cell, causing more positive ions to enter. The excess ion charge travels through small channels to neighboring cells, causing them to contract

Contraction of one cell causes its neighbors to be stretched. Stretched cardiac cells contract

Explanation / Answer

3. Positively charged ions enter a cardiac cell, causing more positive ions to enter. The excess ion charge travels through small channels to neighboring cells, causing them to contract.

It is the concept of depolarization. When any form of impulse strikes the cell, it causes change in membrane potential by changing the ion permeability across the membrane. If the membrane potential reach threshold potential (the minimum potential difference to elicit a response), then the action potential is generated. The fast sodium channels open after reaching the threshold potential causing depolarization of the membrane. This causes net change in membrane potential, whivh travels further.

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