1_A correct statement about biosynthesis of saturated fatty acids containing an

Question

1_A correct statement about biosynthesis of saturated fatty acids containing an even number of carbon atoms (up to 16 carbons) is:

A. the process occurs within mitochondria with the net consumption of NADH.

B. bicarbonate is required and incorporation of 14C from labeled bicarbonate (by the most direct path) would yield fatty acid labeled at any odd numbered carbon.

C. all carbons are derived from acetyl CoA with net requirement of 2 ATP per acetyl CoA consumed.

D. nicotinamide containing cofactors are directly required but flavin containing cofactors are not.

E. the biosynthesis occurs in the cytoplasm with net consumption of acetyl CoA, ATP, and H2O.

.2_ Which of the following statements about acetyl coenzyme A is incorrect?

A. A portion of the molecule consists of phosphopantetheine

B. A thioester bond is present

C. It is a form in which carbon skeletons of fats and carbohydrates enter the citric acid cycle.

D. It is a key intermediate in utilization of energy stored in triacylglycerols

E. It is a key intermediate in the net conversion of fatty acids to carbohydrates in animals

3_Acyl carrier protein:

A. functions as a substrate for acetyl transacylase or malonyl transacylase.

B. is a 77 residue polypeptide containing biotin.

C. is found in the mitochondrial matrix.

D. accepts fatty acyl units from acyl carnitine.

E. transports acetyl units from the mitochondrial matrix to the cytosol for use by the fatty acid synthase multienzyme complex.

Explanation / Answer

1. The answer is E

because the biosynthesis of saturated fatty acids containing an even number of carbon atoms occurs in the cytoplasm with net consumption of acetyl CoA, ATP, and H2O.

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