Genetics A) Below are 4 pedigrees. There is a question about whether New Cow is
ID: 50889 • Letter: G
Question
Genetics
A) Below are 4 pedigrees. There is a question about whether New Cow is the daughter of sire 1 or sire 2. There is no information on the genotypes of Sire 1 or Sire 2, but there is information on a son of Sire 1 (which may be a half-sib of New Cow) and we have genotypes on the son of New Cow and Sire 3.
1)From the genotype data, identify what Sire 1’s likely genotypes are if New Cow is his daughter and Son of Sire 1 is his son?
2)Are the genotypes of Sire 1 consistent with the fact that New Cow is his daughter?
3) If we just consider two markers (marker 1 and 2) and the allele frequency of allele 182 is 0.2, and the allele frequency of 184 is 0.3 and the allele frequency of 225 in marker 2 is 0.1, 232 is 0.3 and 0.2 for 227 what is the probability that New Cow would have the genotypes that she has by chance for these 2 markers?
Sire 1 Sire 2 New Cow New Cow Dam 1 Dam 2 Sire 1 Sire 3 Son of Sire 1 Son of New Cow Dam 3 New CowExplanation / Answer
The genotype of sire can be determined by genotyping 100 to 1000 daughters. The grand progeny is selected based on the index which includes both phenotypic and genotypic information. The fraction of within-family variance of grand-progeny predicted by marker analysis of both son of sire and son of new would be of great help.
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