The poison Antimycin A1 KILLS by blocking the mitochondrial respiratory chain by

Question

The poison Antimycin A1 KILLS by blocking the mitochondrial respiratory chain by blocking the flow of electrons in Complex III from bH and Q (at the Qi site). Regarding the components of the respiratory transports chain listed below, which will be oxidized (make a list) and which will be reduced (make a list) in mitochondria exposed to Antimycin A1: (for some compounds, I gave both components of the redox pair just so as not to give the answer away)

NAD+/NADH

FAD/FADH2

Q/QH2

Cyt C1

Cyt C

CuA/CuA

heme a

heme a3

CuB

Explanation / Answer

NAD+/NADH -it is reduced

FAD/FADH2 - it is reduced

Cyt C1- it is reduced

Cyt C - it is reduced

CuA/CuA- it is oxidised

heme a - it is oxidised

heme a3- i is oxidised

CuB - is oxidised

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