Item 11 Neurotransmitters have an important role in many areas of health, includ
ID: 51320 • Letter: I
Question
Item 11 Neurotransmitters have an important role in many areas of health, including allergic responses, mental health, drug addiction, and pain. Histamine is the neurotransmitter responsible for allergic responses such as hay fever or a red bump that forms from an insect bite. Monoamines such as serotonin are involved in mood, mental illness, and drug addiction. Serotonin, norepinephrine, and dopamine are a group of neurotransmitters collectively called monoamines. A lack of these monoamines has been linked to depression. Depression is treated with drugs that prolong the effect of these neurotransmitters either by preventing the re-uptake of the neurotransmitters, or by inhibiting the enzyme that breaks down these neurotransmitters. Which of the following statements about neurotransmitters are true? The table lists the classifications of three Check all that apply. Fluoxetine inhibits the enzyme that breaks down monoamines. Some drug addictions are the result of dopamine agonists. Dopamine plays a role in feelings of pleasure and pain. MAO inhibitors are examples of monoamine antagonists. A deficiency of serotonin, norepinephrine, and dopamine is associated with depression. Amitriptyline and fluoxetine both prevent the re-uptake of serotonin and norepinephrine. Depression may be treated with monoamine agonists.Explanation / Answer
Serotonin, norepinephrine and dopamine are monoamines which play a very important role in the body. Serotonin is predominantly found in the Gastrointestinal tract (GI Tract), blood platelets and central nervous system. It is believed to promote a feeling of well being and happiness. Norepinephrine plays multiple roles both as a hormone and a neurotransmitter. It helps in creating alertness within the body for any emergency situation. On the contrary dopamine is related to cognitive alertness. Following are the statements which apply to the paragraph above.
"Some drug addictions are the result of dopamine agonists". Common side effects of Dopamine agonists are euphoria which promotes the use of dopmine agonists as drugs.
"Dopamine plays a role in feelings of pleasure and pain"
"MAO inhibitors are examples of monoamine antagonists"
"A deficiency of serotonin, norepinephrine and dopamine is associated with depression"
"Depression may be treated with monoamine agonists".
"A malaria biologist"
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