the acquired capability of self sufficiency in growth signals: a. is generated b
ID: 51602 • Letter: T
Question
the acquired capability of self sufficiency in growth signals:
a. is generated by the mitochondria
b. is found normally in many cell types
c. results from tumor cells generating autocrine signaling
d. is only deregulated in a small percentage of tumors
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what is the best explanation for why most cancer cells express only moderately high levels of potent oncogenes, rather than very high levels?
a. because cancer cells that grow slowly are most successful
b. because cancer cells that grow too fast are found more easily by the immune system
c. because high levels of oncoproteins inhibit angiogeness
d. because high levels of oncoproteins can provoke senescence or apoptosis
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Why can tumor cell necrosis actually promote tumor formation?
a. like apoptosis, necrosis involves the shrinkage of necrotic cells, making more room for the tumor
b. necrosis causes local inflammation, which can promote proliferation
c. necrosis results in subsequent deaths of nearby healthy cells, favoring tumor growth
d. necrosis allows the tumor cell to evade apoptosis.
Explanation / Answer
The acquired capability of self sufficiency in growth signals results from tumor cells generating autocrine signaling. Thus, the option (c) is correct.
The best explanation for why most cancer cells express only moderately high levels of potent oncogenes, rather than very high levels is because high levels of oncoproteins can provoke senescence or apoptosis. Thus, option (d) is correct.
Tumor cell necrosis actually promotes tumor formation because necrosis results in subsequent death of nearby healthy cells, favoring tumor growth. Hence, the option (c) is correct.
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