Acetaminophen is metabolized by which of the following enzyme (s) A. CPY1A2 B. C

Question

Acetaminophen is metabolized by which of the following enzyme (s) A. CPY1A2 B. CYP2E1 C. CYP3A4 D. All the above. Which of the following characteristics can be associated with biotransformation reaction? A. Phase I biotransformation reactions result in addition of -OH, -NH_2 or -SH group to a drug substrate. B. Phase II biotransformation reactions mediate conjugation reaction and add hydrophilic groups like glycine and glucuronic acid. C. Phase I biotransformation reactions always precede Phase II biotransformation reactions for all drug substrates. D. All the above. E. A and B only.

Explanation / Answer

(17) Acetamino phen is metabolized by all of A,B&C

Therefore option (D) is correct.

(18)All of the given statements A,B& C are correct.

Therefore option (D) is correct.

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