Q2. Compared to other diastereomer carbohydrates, what is special structure and

Question

Q2. Compared to other diastereomer carbohydrates, what is special structure and reactivity of glucose that led nature to adopt it as a universal energy currency? Your answer will need to include a 1) discussion of the equilibrium cyclization of glucose, converting from its linear to its cyclized state, 2) drawing the complete reaction mechanism for the interconversion during cyclization and 3) explain how the conformation of glucose bestows upon the special properties compared other carbohydrates, and 4) how these special properties explain why nature chose glucose.

Explanation / Answer

99% of glucose exsist in hemiacetal form ang 1% exsist in open form

hemiacetal form of glucose undergo an intramolecular reaction to form cyclic hemiacetal which is more stable as compare to intermolecular hemiacetals

the 5 & 6 membered rings are generally stable as the stability of cyclic hemiacetals is highly dependent on the size of the ring

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