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3 homework questions 1. Is stem cell research a benefit or an invasion on human

ID: 52843 • Letter: 3

Question

3 homework questions

1. Is stem cell research a benefit or an invasion on human life? Please defend your position with supporting facts and references. ******response should be at least 300 words in length. All sources used, including the textbook, must be referenced; paraphrased and quoted material must have accompanying citations. Any references or citations used should be in APA style. Please include at least two peer-reviewed articles as references.

2. Guinea Pigging refers to soliciting the participation of healthy individuals in clinical drug trials for financial incentives. Do you agree with this practice? Defend your position with supporting facts and references. ****response should be at least 300 words in length. All sources used, including the textbook, must be referenced; paraphrased and quoted material must have accompanying citations. Any references or citations used should be in APA style. Please include at least two peer-reviewed articles as references.

3. Of the three types of boards (Institutional Review Board, Professional Ethics Committee, Community Advisory Board) which would you see the most benefit in being a part of, and why? Discuss your preference in detail. ******response should be at least 300 words in length. All sources used, including the textbook, must be referenced; paraphrased and quoted material must have accompanying citations. Any references or citations used should be in APA style. Please include at least two peer-reviewed articles as references.

Explanation / Answer

1.

Stem cells are the undifferentiated or blank cells that are capable of self renewal. Stem cells divide to produce daughter cells, in which both may be similar to the parent stem cell, or one stem cell and another progenitor cell. During the first stages of our embryonic life, cells divide continuously without being specialised, because they are stem cells.

Progenitor cell is not stem cell, but it is a partially specialised cell. The daughter cells of progenitor cells divide and these daughter cells differentiate to specialised cells. For example, the progenitor cells of bone marrow give rise to more specialised blood cells of different types.

Stem cell research is beneficial from its theraoeutic applications point of view, as treatment with stem cells seems to be promising.

•Stem cell therapy is expected to provide the solution in the treatment of neurodegenerative diseases, diabetes, heart disease, and other conditions where organ regeneration or transplantation is needed.

•The use of differentiated cell lines to test new drugs on each cell type to examine possible interactions in vitro before performing in vivo studies is critical in the development of drugs. Having these cell lines available for research use will reduce the need for research animals.

•Stem cells can be used to repair or generate healthy and functioning specialized cells that can replace diseased or dysfunctional cells.

•It is similar to organ transplantation, but the treatment consists of transplantation of cells instead of organs.

•The most important potential application of human stem cells is the generation of cells and tissues that could be used for cell-based therapies.

•Stem cells, directed to differentiate into specific cell types, offer the possibility of a renewable source of replacement cells and tissues to treat diseases including macular degeneration, spinal cord injury, stroke, burns, heart disease, diabetes, osteoarthritis, and rheumatoid arthritis.

References:

1). Roopa R Nadig. Stem cell therapy-hype or hope?, A review. J Conserv Dent. 2009 Oct-Dec; 12(4): 131–138.

2). G. N. Suma, Madhu Pruthi Arora, Manisha Lakhanpal. Stem cell therapy: A novel treatment approach for oral mucosal lesions, J Pharm Bioallied Sci. 2015 Jan-Mar; 7(1): 2–8.