A) What is the genotype of a pure-breeding green parakeet strain? B) Using the s

Question

A) What is the genotype of a pure-breeding green parakeet strain?

B) Using the same information in the question above, what is the genotype of a pure-breeding red strain of parakeet? (may have more than one).

2.) Human ABO blood type is determined by three alleles (IA, IB, and i) whose gene products modify the H antigen produced by protein activity of an independently assorting H gene. A rare abnormality known as the "Bombay phenotype" is the result of epistatic interaction between the gene for the ABO blood group and the H gene. Individuals with the Bombay phenotype appear to have blood type O based on the inability of both anti-A antibody and anti-B antibody to detect an antigen. The apparent blood type O in the Bombay phenotype is due to the absence of H antigen as a result of homozygous recessive mutations of the H gene. Individuals with the Bombay phenotype have the hh genotype. Use the information above to make predictions about the outcome of the following cross: IAIBHh X IAIBHh. Check all that apply:

a) AB

b) A

c) B

d) O

Explanation / Answer

1. For answering this part , biosynthetic pathway is required.

2. Hh crossed with Hh will give HH, Hh and hh in the ratio 1:2:1. So, chances of having hh antigen are 1/4.

IAIBHh X IAIBHh

From the given cross, individuals with blood type, IAIA, IAIB ,IBIB in the ratio 1:2:1
and O can be produced.

Chances of having A blood group, 1/4*3/4 = 3/16

Chances of having B blood group, 1/4*3/4 = 3/16

Chances of having AB blood group, 1/2 * 3/4 = 3/8 or6/16

Chances of having O blood group, 1/4 = 4/16

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