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Albanism is a tratit caused by homozygosity for a recessiveallele a. In Humans ,

ID: 5829 • Letter: A

Question

Albanism is a tratit caused by homozygosity for a recessiveallele a. In Humans , the frequency of albino individuals is about1 in 20,000 or 0.00005. Use A for the dominant non-albinoallele. a) what is the frequency of the a allele? of the Aallele? b?Estimate the frequencies of the other two possiblegenotypes. c)In a population of 1,000,000 people, how many do we expectto be carriers for albinism, but not actually be albino? Albanism is a tratit caused by homozygosity for a recessiveallele a. In Humans , the frequency of albino individuals is about1 in 20,000 or 0.00005. Use A for the dominant non-albinoallele. a) what is the frequency of the a allele? of the Aallele? b?Estimate the frequencies of the other two possiblegenotypes. c)In a population of 1,000,000 people, how many do we expectto be carriers for albinism, but not actually be albino?

Explanation / Answer

a)      what is the frequency of the aallele? of the A allele?

homozygosityfor a recessive allele-------- a

thedominant non-albino allele.---------A

q2 =1 /20,000=0.00005

q=0.007----------a-------Rcessive allele frequency

p=0.993------------A--------dominant allele frequency

b?Estimatethe frequencies of the other two possible genotypes.

p=0.993

Dominanthomozygotes –AA--------= 0.993 x0.993=0.9860

HETEROZYGOTES--------2Aa= 2 x0.993 x0.007=0.014

c)In apopulation of 1,000,000 people, how many do we expect to becarriers for albinism, but not actually be albino?

14,000--answer

carriers foralbinism are heterozygotes = 0.014 x1,000,000=14,000

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