Which of the following statements are true (choose one or more answers): a) Afte

Question

Which of the following statements are true (choose one or more answers): a) After building the profile HMM, each sequence will have a unique alignment with that HMM. b) When aligning a sequence with the profile HMM, a shift in the alignment will not change the alignment score. c) The most probable path of how a sequence aligns to an HMM can be obtained from the forward algorithm. d) Any sequence can be represented by a path through any profile HMM model. e) The total probability of a sequence coming from a profile HMM is the summation of scores from all possible paths.

Explanation / Answer

a / d / e are true.

Its not always forward algorithm.

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