List the three main stages of T cell development. ,

ID: 59684 • Letter: L

Question

List the three main stages of T cell development. ______________, ______________ and ______________

List the three main surface molecules that are used to define the major stages of T cell development? ______________, ______________ and ______________

List the two chains of the T cell receptor found on developing and mature CD4 and CD8 T cells ______________ and ______________

What surface molecule does the T cell receptor interact with during positive and negative selection? ________________________

At what stage of T cell development is the T cell receptor finally expressed on the cell surface?

Explanation / Answer

List the three main stages of T cell development. selection, differentiation and maturation.

List the three main surface molecules that are used to define the major stages of T cell development: CD4 , CD8 and Memory T cells.

List the two chains of the T cell receptor found on developing and mature CD4 and CD8 T cells CD4 glycoprotein and CD8 glycoprotein.

Double positive cells (CD4+ and CD8+ ) interact with Class II MHC during positive selection and Class I MHC peptides during negative selection.

During activation stage T cell receptor is finally expressed.

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List the three main stages of T cell development. ______________, ______________

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List the three main stages of T cell development. ,