A 45 y/o IV drug user comes to you with complaints of general malaise and says h

Question

A 45 y/o IV drug user comes to you with complaints of general malaise and says he is constantly getting sick. He says that before the last 6 months he only recalled getting sick one other time in his life; a week after attending Burning Man 2005, when he had flu-like symptoms for 4 weeks, but was never treated. Now he can only fight the infection with the help of long courses of antibiotics. You do send a sample of his blood to the hematologist and find that he only has 250 CD4+ cells per microliter. (a) What do you think is the microbe responsible for causing this problem? (b) What does rt-PCR stand for and why is it used for diagnosis of this infection? (c) What name has been used to describe his current symptomatic disease state? (d) What was it called when he got sick after Burning Man? (e) Name two classes of drugs he could be placed on.





A 45 y/o IV drug user comes to you with complaints of general malaise and says he is constantly getting sick. He says that before the last 6 months he only recalled getting sick one other time in his life; a week after attending Burning Man 2005, when he had flu-like symptoms for 4 weeks, but was never treated. Now he can only fight the infection with the help of long courses of antibiotics. You do send a sample of his blood to the hematologist and find that he only has 250 CD4+ cells per microliter. (a) What do you think is the microbe responsible for causing this problem? (b) What does rt-PCR stand for and why is it used for diagnosis of this infection? (c) What name has been used to describe his current symptomatic disease state? (d) What was it called when he got sick after Burning Man? (e) Name two classes of drugs he could be placed on.





A 45 y/o IV drug user comes to you with complaints of general malaise and says he is constantly getting sick. He says that before the last 6 months he only recalled getting sick one other time in his life; a week after attending Burning Man 2005, when he had flu-like symptoms for 4 weeks, but was never treated. Now he can only fight the infection with the help of long courses of antibiotics. You do send a sample of his blood to the hematologist and find that he only has 250 CD4+ cells per microliter. (a) What do you think is the microbe responsible for causing this problem? (b) What does rt-PCR stand for and why is it used for diagnosis of this infection? (c) What name has been used to describe his current symptomatic disease state? (d) What was it called when he got sick after Burning Man? (e) Name two classes of drugs he could be placed on.

Explanation / Answer

a. West Nile virus a mosquito-borne zoonotic arbovirus could be the possible microbe responsible for such symptoms.As according to news and literature West nile fever is the outbreak in burning man event.

b. rt-PCR is real-time polymerase chain reaction This method is used to detect WNVbecause of its high sensitivity.

This test directly detects WNV RNA in serum and CSF. WNV viremia peaks at about the time of symptom onset and rapidly fades to undetectable levels. Thus, PCR assays can detect WNV RNA in clinical samples as early as several days before symptom onset, prior to seroconversion.

c.  The name used to describe his current symptomatic disease state is West Nile fever (WNF)

d. postpalaya dust cough

e.Antibiotics are not effective against viral illnesses . Antiviral drugs and Immunoglobulins can be used.

Related Questions

Navigate

• Browse (All)
• Browse A
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.