Suppose that a single base-pair deletion occurred in the part of the gene that c

Question

Suppose that a single base-pair deletion occurred in the part of the gene that corresponds to the partial mRNA above, resulting in this partial amino acid sequence:

(N-term-...V-G-R-T-K-A...-C-term)

Which new partial mRNA sequences would be consistent with this change?

Choose two. Bases surrounding the deletion are underlined.

5' - UG | GUC | GGG | AGA | ACG | AAA | GCG | C - 3' 5' - UG | GUC | GGC | AGA | ACG | AAA | GCG | C - 3' 5' - UG | GUC | GGC | GGA | ACG | AAA | GCG | C - 3' 5' - UG | GUC | GGC | GAA | ACG | AAA | GCG | C - 3' 5' - UG | GUG | GCG | AGA | ACG | AAA | GCG | C - 3'

Explanation / Answer

N-term-...V-G-R-T-K-A...-C-term

N - term-- Val- Gly- Arg - Thr - Lys - Ala -- C -term

sequence 1: GTC - GGG - AGA - ACG - AAA - GCG

If a base G is changed to C, then the sequence would be :

Hence, sequences 1 and 2 are correct.

5' - UG | GUC | GGG | AGA | ACG | AAA | GCG | C - 3' 5' - UG | GUC | GGC | AGA | ACG | AAA | GCG | C - 3'

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