Often gene expression is regulated by small RNAs. For example, the Fbx15 gene ca

Question

Often gene expression is regulated by small RNAs. For example, the Fbx15 gene can be regulated by a complementary miRNA. What would you expect to happen to the expression of Fbx15 if DNA methylation increased upstream of the region encoding the miRNA?

Fbx15 transcript abundance would increase.

Fbx15 transcript abundance would decrease

Fbx15 transcript abundance would be unaffected

Can not be predicted from the information given

Fbx15 transcript abundance would increase.

Fbx15 transcript abundance would decrease

Fbx15 transcript abundance would be unaffected

Can not be predicted from the information given

Explanation / Answer

Genome imprinting is an epigenetic phenomenon by which certain genes can be expressed based on their parental origin. Genome imprinting involves methylation of DNA (deoxyribonucleic acid) and histone modification to achieve expression of genes without genetic alteration. Methylation would probably increase the expression of miRNA. So, Fbx15 transcription would decrease.

Hence, the correct option is Fbx15 transcript abundance would decrease

Related Questions

Navigate

• Browse (All)
• Browse O
• Subjects

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.