stay away from the leaves of dichapetalum cymosum,a South African plant. Animals

Question

stay away from the leaves of dichapetalum cymosum,a South African plant. Animals that eat the leaves have convulsions and usually die shortly thereafter.One of the most pronounced effects of poisoning is a marked elevation in citrate concentration and a blockage of the citric acid cycle in the organs of the affected animal.The poison detected in the tissues of animals is fluorocitrate

b) Identify the enzyme in the citric acid cycle you suspect is affected by fluorocitrate by identifying the reaction this enzyme catalyst.

Explanation / Answer

When citrate accumulates we can say tht the enzyme aconitase is inhibited by fluorocitrate. This makes citrate accumulate and stops the TCA cycle from going forward.

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