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What phenotype changes do you expect in flies homozygous for loss-of-function mu

ID: 65285 • Letter: W

Question

What phenotype changes do you expect in flies homozygous for loss-of-function mutations in the following genes: Part A Kruppel

a. Kruppel polarity defects in embryonic and adult structures.

b.shift in the identity of the third thoracic segment and the first abdominal segment to an identity resembling the second thoracic segment.

c.loss of head, thorax, and anterior abdominal segments.

d.loss of the odd-numbered segments.

Part B odd-skipped

a.odd-skipped polarity defects in embryonic and adult structures.

b.shift in the identity of the third thoracic segment and the first abdominal segment to an identity resembling the second thoracic segment.

c.loss of the odd-numbered segments.

d.all of the above.

e.none of the above.

Part C hedgehog

a.hedgehog defects within segments lead to malformed embryonic and adult structures.

b.shift in the identity of the third thoracic segment and the first abdominal segment to an identity resembling the second thoracic segment.

c.loss of the odd-numbered segments.

d.all of the above.

e.none of the above.

Part D Ultrabithorax

a.Ultrabithorax polarity defects in embryonic and adult structures.

b.shift in the identity of the third thoracic segment and the first abdominal segment to an identity resembling the second thoracic segment.

c.loss of eyes.

d.loss of wings and legs.

e.all of the above.

Explanation / Answer

A c.loss of head, thorax, and anterior abdominal segments B c.loss of the odd-numbered segments. C a.hedgehog defects within segments lead to malformed embryonic and adult structures. D b.shift in the identity of the third thoracic segment and the first abdominal segment to an identity resembling the second thoracic segment.

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