3. After working in a mushroom farm for several months, a worker develops these

Question

3. After working in a mushroom farm for several months, a worker develops these symptoms: hives, edema, and swollen lymph nodes. (a) What do these symptoms indicate? (b) What mediators cause these symptoms? (c) How may sensitivity to a particular antigen be determined? (d) Other employees do not appear to have immunological reactions. What could explain this? (Hint: The allergens is conidiospores from molds growing in the mushroom farm.) 3. After working in a mushroom farm for several months, a worker develops these symptoms: hives, edema, and swollen lymph nodes. (a) What do these symptoms indicate? (b) What mediators cause these symptoms? (c) How may sensitivity to a particular antigen be determined? (d) Other employees do not appear to have immunological reactions. What could explain this? (Hint: The allergens is conidiospores from molds growing in the mushroom farm.) 3. After working in a mushroom farm for several months, a worker develops these symptoms: hives, edema, and swollen lymph nodes. (a) What do these symptoms indicate? (b) What mediators cause these symptoms? (c) How may sensitivity to a particular antigen be determined? (d) Other employees do not appear to have immunological reactions. What could explain this? (Hint: The allergens is conidiospores from molds growing in the mushroom farm.)

Explanation / Answer

These symptoms indicate the occurrence of hypersensitivity (localized anaphylaxis) reaction. It is mediated by mast cells particularly. Serum mast cell tryptase help to diagnose the same with increased sensitivity and specificity (Brown et al.,2004).

Other employees do not have immunological reaction because they are not sensitive to the same allergen.

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