As a research physiologist you are beig rediculously over founded to study how t

Question

As a research physiologist you are beig rediculously over founded to study how the kindey handles a new drug. substance Q. your subject was infused with a constant amount of the drug and inulin producing plasma concentration 6mmol/l substance Q: and a plasma inulin concentration of 5mmol/l. over the course of 30 min of experiment your subject produces 60 ml volume of urine. in that urine you meausre a substance Q concentration of 1440mmol/l and inulin concentration of 300mmol/l. by what mechanism is substance Q being cleared by your subject's kindey? show all your work and explain the derivation of your conclusions. ( show all your alculation)

Explanation / Answer

The mechanism by which the substance Q is being cleared by subject's kidney is renal clearance. The excretion of substance Q in the urine is a result of:

a. Glomerular filtration

b. Active tubular secretion, and

c. Tubular reabsorption

This type of clearance by kidneys is indicative of a person's renal function.

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